The study provide a detailed longitudinal evaluation of the gluco-insulinemic assessment of
pregnant PCOS women under metformin treatment. 47 non diabetic Polycystic Ovary Syndrome
(PCOS) women became pregnant during metformin treatment and continued taking the drug during
gestation. An oral glucose tolerance test and euglycaemic hyperinsulinaemic clamp were
performed at each trimester of gestation.