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More info
You can access this
clinical trial
if you have
Lung Cancer, Non Small Cell Lung Cancer (NSCLC), Breast Cancer or Estrogen Receptor Breast Cancer
and you are
between 18 and 90
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

The purpose of this study is to evaluate the effect of food on the pharmacokinetics (PK) of the experimental drug, entinostat, in women with breast cancer and men and women with non-small cell lung cancer. The safety and tolerability of entinostat will also be evaluated when entinostat is given by itself as well as with the approved drugs, exemestane (Aromasin®) or erlotinib (Tarceva®). A biomarker (chemical "marker" in the blood/tissue that may be related to your response to the study drug) will also be tested.

Provided treatments

  • Drug: entinostat
  • Drug: entinostat
  • Drug: Erlotinib
  • Drug: Erlotinib
  • Drug: Exemestane
  • Drug: Exemestane

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01594398. The sponsor of the trial is Syndax Pharmaceuticals and it is looking for 14 volunteers for the current phase.
Official trial title:
A Phase I Study to Assess the Food Effect on the Pharmacokinetics of Entinostat in Postmenopausal Women With Locally Recurrent or Metastatic ER+ Breast Cancer and Men and Women With Progressive Non-Small Cell Lung Cancer