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Your journey
1What's a trial
2Find
3Review
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More info
You can access this
clinical trial
if you have
Cardiovascular Disease
and you are
over 18
years old
3
This is a trial in the final phase before the treatment is released on the market.
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The purpose

The Cardiovascular Inflammation Reduction Trial (CIRT) is a randomized clinical trial investigating whether taking low-dose methotrexate reduces heart attacks, strokes, or death in people with type 2 diabetes or metabolic syndrome that have had a heart attack or multiple coronary blockages. This trial is funded by the National Heart, Lung, and Blood Institute (NHLBI)/National Institutes of Health (NIH).

Provided treatments

  • Drug: Methotrexate
  • Drug: Placebo

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01594333. The sponsor of the trial is Brigham and Women's Hospital and it is looking for 4786 volunteers for the current phase.
Official trial title:
A Randomized, Double-blind, Placebo-controlled, Event-driven Trial of Weekly Low-dose Methotrexate (LDM) in the Prevention of Cardiovascular Events Among Stable Coronary Artery Disease Patients With Type 2 Diabetes or Metabolic Syndrome