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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Estrogen-receptor Positive Invasive Metastatic Breast Cancer
and you are
over 18
years old
This is a second phase trial assessing
efficacy and side effects of the new treatment.
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The purpose

This is a Phase II investigator-Initiated trial of the Investigational Drug, Ruxolitinib, in combination with Exemestane in patients with estrogen-receptor positive advanced breast cancer. The objective of this study is to determine the preliminary safety and efficacy of the combination of exemestane and Ruxolitinib (INCB018424).

Provided treatments

  • Drug: Ruxolitinib
  • Drug: Exemestane

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01594216. The sponsor of the trial is Abramson Cancer Center of the University of Pennsylvania and it is looking for 29 volunteers for the current phase.
Official trial title:
A Phase II Trial Of The JAK-Inhibitor Ruxolitinib (INCB018424) In Combination With Exemestane For Patients With Estrogen Receptor (ER) Positive Advanced Breast Cancer)