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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Patent Ductus Arteriosus
and you are
under 1
years old
This is a trial in the final phase before the treatment is released on the market.
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The purpose

Patent ductus arteriosus (PDA) is a very common condition in immature newborn babies and it has been associated to morbidity and mortality. Ibuprofen is the drug of choice for PDA treatment according to the last version of the Cochrane review. Nowadays the best dose regimen for ibuprofen remains uncertain. The investigators aim to perform a randomized controlled clinical trial to assess whether echocardiographically guided PDA ibuprofen treatment versus standard treatment could reduce the number of doses of ibuprofen without increasing the reopening rate and reducing the side effects associated to this medication.

Provided treatments

  • Drug: Ibuprofen EchoG
  • Drug: Standard ibuprofen treatment

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01593163. The sponsor of the trial is Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz and it is looking for 49 volunteers for the current phase.
Official trial title:
Randomised Controlled Clinical Trial of Echocardiographically Guided Versus Standard Ibuprofen Treatment for Patent Ductus Arteriosus: a Pilot Study