This clinical trial investigates relative benefits (clinical effectiveness and quality of
life) of two extraction patterns when lower first permanent molars (FPM) are extracted in
children The study objectives are to determine whether compensating extraction of upper FPMs
following loss of lower FPMs in children is of benefit. The particular benefits being
investigated are related to the resulting occlusion, patient experience and oral health
related quality of life. The follow up will extend over a period of 5 years or until the
patient is 14 years of age - whichever is earlier.