Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Obsessive Compulsive Disorder, Major Depressive Disorder or Epilepsy
and you are
between 18 and 70
years old
The phase for this study is not defined.
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The purpose

We propose to study approach/avoidance behavior as measured by the Approach Avoidance task in 20 epilepsy patients undergoing implementation of depth electrodes for seizure monitoring in the Epilepsy Monitoring Unit at MGH. We will also study the effects of VC/VS electrical stimulation on approach-avoidance conflict in 20 adult patients who have undergone DBS implantation for severe MDD and/or OCD. There are 100-200 patients in the world with DBS electrodes in the VC/VS, and our research team cares for more than any other institution. Both participant groups will be assessed with respect to reward-aversion decision conflict using the task. The task will be performed with concurrent EEG recordings in DBS patients, and with continuous recording through our invasive neurophysiology rig in EMU subjects.

Provided treatments

  • Device: Deep Brain Stimulator
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Locations near you

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Tris trial is registered with FDA with number: NCT01590862. The sponsor of the trial is Massachusetts General Hospital and it is looking for 60 volunteers for the current phase.
Official trial title:
ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators