- Although aging process appears to be generally characterized, investigators have been
paid much attention to the specific target molecules, which leads to discover the
clinical markers of the senescence. The present study is to investigate the clinical and
biological profile of cognitive decline and functional cardiac senescence in healthy
middle aged and elderly Korean volunteers.
- This study was conducted as a cross-sectional, single-center, comparative clinical
- Each volunteer was given informed consent for checking cognition and cardiac function.
Blood and urine samples were collected to analyze genome, proteome, and metabolome to
assess cognition and cardiac function of its muscle enzymes.