Fluoride toothpaste has been associated not only with declining dental caries prevalence but
also with an increase in dental fluorosis. In the balance of benefits/risks of fluoride
toothpaste use, the purpose of this study is to evaluate the availability of fluoride
concentration in the mouth (biofilm fuild), as an indicator of fluoride benefits (anticaries
effect), and the fluoride concentration in urine, as an indicator of fluoride absorption from
ingested toothpastes (with potential to cause dental fluorosis), in a sample of young
Brazilian children using toothpaste formulations representative of those available and most
used by this age-group.