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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Nicotine Dependence
and you are
between 18 and 40
years old
The phase for this study is not defined.
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The purpose

The proposed clinical studies will analyze the interactions between progesterone, nicotine, alterations in endocrine hormones, mood and cardiovascular measures. It is hypothesized that the administration of progesterone at a dose that mimics luteal phase levels in normal cycling women will diminish the positive subjective effects of nicotine, as has been consistently observed for cocaine. This novel approach could have direct implications for facilitating smoking cessation treatment in women of reproductive age

Provided treatments

  • Drug: Intravenous Nicotine
  • Drug: Progesterone

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01589081. The sponsor of the trial is Mclean Hospital and it is looking for 45 volunteers for the current phase.
Official trial title:
Effects of Progesterone on IV Nicotine-Induced Changes in Hormones and Subjective Ratings of Stimulant Drug Effect