The study consists of measurement of antidepressant-induced excessive sweating and its
treatment with an experimental medication, glycopyrrolate (approved to treat ulcers), which
will be added to the antidepressant. This is an open-label study (no placebo group or
concealment of the nature of the treatment) that will last 8 weeks, including two weeks of
baseline measurement without treatment with the study medication followed by six weeks of
treatment with the study medication. The study is pilot study by Dr. Rajnish Mago that is
based on the hypothesis that glycopyrrolate will be effective in reducing the severity of
excessive sweating caused by antidepressant treatment, and will have minimal side-effects.