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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Bipolar I Disorder or Bipolar II Disorder
and you are
between 18 and 65
years old
The primary goal of this phase is to monitor the long-term effects.
The treatment is already on the market.
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The purpose

The purpose of this study is to compare which of the two mood stabilizers (drugs that help to steady/stabilize mood in patients with bipolar disorder (BD)), lithium and divalproex, is more effective in patients with bipolar disorder over 26 weeks. The study will also compare if lithium or divalproex used alone versus lithium or divalproex used with quetiapine versus lithium or divalproex used with lamotrigine is more effective when symptoms of depression develop.

Provided treatments

  • Drug: Lithium
  • Drug: Divalproex
  • Drug: Lamotrigine
  • Drug: Quetiapine

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01588457. The sponsor of the trial is The University of Texas Health Science Center at San Antonio and it is looking for 112 volunteers for the current phase.
Official trial title:
Sequential Multiple Assignment Randomized Treatment (SMART) for Bipolar Disorder