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Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Anterior Cruciate Ligament Reconstruction or Regional Anesthesia, Saphenous Nerve Block
and you are
between 16 and 65
years old
The primary goal of this phase is to monitor the long-term effects.
The treatment is already on the market.
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The purpose

For patients undergoing Anterior Cruciate Ligament reconstruction surgery, the postoperative period can be a painful experience without adequate pain management. Hence the investigators propose a randomized controlled clinical study, investigating prolonged saphenous nerve blocks. Patients will be randomized to receive saphenous nerve blocks with or without dexamethasone, a corticosteroid used to prolong analgesia. Depending on the randomized treatment assignment, patients may receive one of the following: 1. 13 ml of 0.5% bupivacaine, a local anesthetic (no dexamethasone); 2. 13 ml of 0.5% bupivacaine mixed with 1 mg of dexamethasone; 3. 13 ml of 0.5% bupivacaine mixed with 4 mg of dexamethasone. Patients will be followed postoperatively. Following admission to the recovery room, data collectors will ask patients to rate their pain on a scale of 0-10 until discharge. Data collectors will also record patient satisfaction, pain medication use and any side effects experienced (i.e. nausea and vomiting). Patients will then be contacted on postoperative days 1, 2 and 14 and asked questions about their general well-being.

Provided treatments

  • Drug: Bupivacaine Only
  • Drug: Bupivacaine with 1 mg of Dexamethasone
  • Drug: Bupivacaine with 4 mg of Dexamethasone

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01586806. The sponsor of the trial is Hospital for Special Surgery, New York and it is looking for 195 volunteers for the current phase.
Official trial title:
Postoperative Analgesia Comparing Subsartorial Saphenous Nerve Block With and Without Dexamethasone in ACL Reconstruction