Aim of the study is to evaluate the effects, on microcirculation of septic patient, of three
types of RBCs: 1- fresh standard RBCs (storage <10 days); 2-leukodepleted RBCs and 3-old
standard RBCs (storage >15 days) respectively. Before and 1 hour after the transfusion,
microcirculation is evaluated using Sidestream Dark Field Imaging (SDF) and Near InfraRed
Spectroscopy (NIRS) with vascular occlusion test. We also monitor temperature, heart rate,
mean blood pressure, hemochrome, blood gases, blood lactates and SOFA score.