The investigators hypothesize that exercise in postmenopausal breast cancer survivors will
result in an increase in the plasma concentrations of angiostatic factors and a decrease in
the plasma concentrations of angiogenic factors. Exercise is expected to result in a
circulating angiostatic phenotype that inhibits adipose tissue mass, growth of breast cancer
tumor, growth of microscopic residual disease after breast cancer resection, decreases rates
of local-regional recurrence, decreases rates of distant recurrence, and increases survival.