The purpose of this study is to prospectively assess whether Desmopressin, given for a period
of month to patients after radical cystectomy with orthotopic bladder reconstruction,
improves and lowers the rate of nocturnal enuresis.
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Full eligibility criteria for NCT01582542
Ages eligible for Study
18 Years and older
Genders eligible for Study
Accepts Healthy Volunteers
Age above 18
Able to give informed consent
Patients afte radical cystectomy with orthotopic bladder reconstruction with night time incontinence
Patients with after radical cystectomy with orthotopic bladder reconstruction with daytime urinary incontinence
Patients already treated with Desmopressin due to other reasons.
Patients with an allergy or insensitivity to Desmopressin.
Patients with known hyponatremia
Patients with severe chronic renal failure and creatinine clearance of below 50 cc/sec.
Patients with severe congestive heart failure
Patients with active urinary tract infection
Patients taking drug therapy which can interact with Desmopressin and affect it's action.Examples include Diuretics, Tricyclic antidepressants, Carbamezapine and Chlorpropamide AND Indomethacin.
Patients with an indwelling urinary catheter.
All locations for NCT01582542
Institute of Urology, Rabin Medical Cetner
Petah Tiqva, Petach Tiqva, Israel, 49100
View full eligibility
Tris trial is registered with FDA with number: NCT01582542. The sponsor of the trial is Rabin Medical Center and it is looking for 50 volunteers for the current phase.
Official trial title: Usage of Desmopressin fo Improving Nocturnal Enuresis in Patients After Radical Cystectomy With Orthotopic Bladder Reconstruction
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