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Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Keratoconus or Corneal Ectasia
and you are
over 18
years old
This is a trial in the final phase before the treatment is released on the market.
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The purpose

Corneal collagen crosslinking (CXL) has been proposed as an effective method of reducing progression of both keratoconus and corneal ectasia after surgery, as well as possibly decreasing the steepness of the cornea in these pathologies. During previous studies of the CXL procedure, the surface epithelial cells have been removed. Transepithelial crosslinking in which the epithelium is not removed has been proposed to offer a number of advantages over traditional crosslinking including an increased safety profile by reducing the risk for infection as no epithelial barrier will be broken, faster visual recovery and improved patient comfort in the early postoperative healing period.

Provided treatments

  • Drug: Riboflavin
  • Drug: Riboflavin

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01464268. The sponsor of the trial is Cornea and Laser Eye Institute and it is looking for 160 volunteers for the current phase.
Official trial title:
Transepithelial Corneal Collagen Crosslinking for Keratoconus and Corneal Ectasia