The purpose of this study is to find the heparinization method, which
1. affect the heparin-protaminsulfate ratio in the best way to achieve haemostasis
2. gives the smallest change in endogenous thrombin potential (ETP)postoperative compared
to preoperative (deltaETP) as an indicator for haemostatic activation during cardiac
The hypothesis is that the deltaETP is larger in the Haemochron Signature Elite group than in
the Hepcon-group because of the heparinization-method. Therefore there is a potential higher
risk for use of bloodproducts postoperatively.