This study is designed to observe the safety and concentrations of PF-05297909 and proteins
in both blood and cerebrospinal fluid after a single dose of PF-05297909 in healthy adults.
Drug: PF-05297909 25 mg
Drug: PF-05297909 100 mg
Drug: PF-05297909 250 mg
Drug: PF-05297909 525 mg
Drug: PF-05297909 525 mg
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Locations near you
Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Full eligibility criteria for NCT01462851
Ages eligible for Study
18 Years to 55 Years
Genders eligible for Study
Accepts Healthy Volunteers
For Healthy adult volunteers: healthy male and/or female subjects of non child bearing potential between the ages of 18 and 55 years, inclusive. (Healthy is defined as no clinically relevant abnormalities identified by a detailed medical history, full physical examination, including blood pressure and heart rate measurement, 12 lead ECG and clinical laboratory tests.)
Evidence or history of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or allergic disease (including drug allergies, but excluding untreated, asymptomatic, seasonal allergies at time of dosing)
All locations for NCT01462851
United States (2)
Glendale, California, United States, 91206
Pfizer Investigational Site
New Haven, Connecticut, United States, 06511
View full eligibility
Tris trial is registered with FDA with number: NCT01462851. The sponsor of the trial is Pfizer and it is looking for 51 volunteers for the current phase.
Official trial title: A Phase 1, Randomized Investigator-And-Subject-Blind, Sponsor Open, Placebo Controlled Two-Part Study To Characterize The Pharmacokinetics And Pharmacodynamics Of Single Doses Of Pf-05297909 In Healthy Adult Subjects
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