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More info
You can access this
clinical trial
if you have
Type 2 Diabetes Mellitus
and you are
between 18 and 80
years old
3
This is a trial in the final phase before the treatment is released on the market.
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The purpose

The purpose of this study is to examine the insulin-sparing effect of sitagliptin 100 mg once-daily compared with placebo over 24 weeks in participants with type 2 diabetes mellitus who have inadequate glycemic control on insulin alone or in combination with metformin. The primary hypothesis of this study is that after 24 weeks, sitagliptin reduces the dose of insulin relative to placebo.

Provided treatments

  • Drug: Sitagliptin
  • Drug: Comparator: Placebo
  • Biological: Insulin Glargine
  • Drug: Metformin

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01462266. The sponsor of the trial is Merck Sharp & Dohme Corp. and it is looking for 660 volunteers for the current phase.
Official trial title:
A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Study the Safety and Insulin-Sparing Efficacy of the Addition of Sitagliptin in Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Insulin Alone or in Combination With Metformin