This study will test the idea that using an experimental mouth rinse after each time you
brush your teeth will result in a healthier mouth than using the regular mouth rinse.
Participants will be expected to avoid oral hygiene (like brushing teeth or using mouthwash)
for at least 12 hours before each visit and will not be allowed to eat, drink or smoke for at
least 4 hours before each visit.
At the first visit, the study will be explained to you in detail and you will be allowed to
ask any questions you may have before signing a consent form. You will complete a
medical/dental history and the dentist will examine your mouth, during which he will poke
your gums and scrape some plaque off your teeth for testing. If you do not meet the
requirements to continue in the trial, you will be told that you do not need to return for
If you meet requirements to continue, you will have an equal chance of being assigned to use
either of the two mouth rinses being studied. You will be given a diary, toothbrush,
toothpaste, and your assigned mouth rinse, with instructions on how they must be used.
You will be instructed not to use any unassigned oral care products and to follow your usual
eating habits. You will be given appointments to return two times within the next four weeks.
At those visits, the staff will check to make sure you're following the instructions and ask
how you're feeling, and the dentist will do the same thing he did during the first visit.