A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Assess the Safety and
Efficacy of TD-1211 in Subjects with Opioid-Induced Constipation
We will connect you to the doctor responsible for this trial and help you get more information.
Locations near you
Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Full eligibility criteria for NCT01459926
Ages eligible for Study
18 Years to 65 Years
Genders eligible for Study
Accepts Healthy Volunteers
History of constipation with onset after initiation of opioid therapy
Self-reported OIC of approximately 3 spontaneous bowel movements (SBMs) per week or less for each week over at least the previous two week period
Have used chronic opioids with a total daily dose ≥30 mg of morphine equivalent units
(MEU, Appendix 7) for the 12 weeks preceding the Screening Visit. Subjects should have used a stable daily regimen of opioids for at least the 2 weeks preceding the Screening Visit
Willing to stop all laxatives and other bowel regimens with the exception of bisacodyl/enema treatment allowed per protocol throughout the OIC confirmation, treatment, and follow-up periods
Have participated in a clinical trial of an investigational drug or medical device within 30 days prior to Screening
Have any condition that may affect drug absorption, (e.g., previous GI surgery)
Any other condition which, in the opinion of the investigator, could confound or interfere with evaluation of safety or tolerability of the investigational drug, or prevent compliance with the study protocol
All locations for NCT01459926
United States (1)
G and L Research, LLC
Foley, Alabama, United States, 36535
View full eligibility
Tris trial is registered with FDA with number: NCT01459926. The sponsor of the trial is Theravance Biopharma and it is looking for 217 volunteers for the current phase.
Official trial title: A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Efficacy of TD-1211 in Subjects With Opioid-Induced Constipation
1What's a trial
4Get in touch
What's a trial
Not sure you're well informed about clinical trials? Learn more about their benefits, risks and other important details.
Enter your details like condition, age, gender and other preferences and we will show you a list of all relevant clinical trials.
Review the summary of the selected clinical trial and all the locations near you in order to see if it's of interest to you.
Get in touch
You've found an interesting trial? We'll need a bit more information about you so we can connect you to the doctor in charge.
Some people want to consult their doctor before considering participation in a clinical trial. This is absolutely normal as your doctor should know your medical history and should be able to advise you. If you want you can easily share the information for this trial with your doctor by clicking on the button below.