This trial is terminated!
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Your journey
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More info
You can access this
clinical trial
if you have
Transfusion-dependent β-thalassemia Patients or Cardiac Iron Overload
and you are
over 18
years old
2
This is a second phase trial assessing
efficacy and side effects of the new treatment.
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The purpose

The primary efficacy endpoint of this interventional study was to evaluate the number of patients achieving a complete response (CR), defined as patients switching from intensive deferasirox -DFO treatment, at any time point during the 24 months of study, to deferasirox monotherapy based on improvement in the cardiac magnetic resonance imaging (MRI) T2* value to >10ms, and continue to maintain their MRI T2* to values >10 msec.

Provided treatments

  • Drug: Deferasirox
  • Drug: Deferoxamine (DFO)

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01459718. The sponsor of the trial is Novartis Pharmaceuticals and it is looking for 32 volunteers for the current phase.
Official trial title:
A Multicenter Open Label Phase II Study to Evaluate the Safety and Efficacy of Deferasirox in Combination With Deferoxamine Followed by Transitioning to Deferasirox Monotherapy in β-thalassemia Patients With Severe Cardiac Iron Overload