Objective: To evaluate the influence of dietary sodium reduction on body fluid volume and
inflammatory state in hemodialysis (HD) patients.
Design: Prospective controlled randomized study. Setting: Dialysis Unit of Botucatu Medical
School Hospital, Sao Paulo State University, Brazil.
Patients: Adult patients on HD for at least 30 days and C-reactive protein (CRP) ≥ 0.7 mg/dl
were randomly allocated into two groups: Group A: 21 patients treated with a 2g sodium
restriction in their habitual diet, and Group B: 18 controls. Inflammatory, biochemical,
hematological and nutritional markers, as well as dialysis dosage were assessed at baseline
and after 8 and 16 weeks.