This trial is completed!
Search for a recruiting clinical trial for your condition
Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Nonhematologic Malignancies or Lymphoma
and you are
over 18
years old
This is an early phase trial to determine
the dosage and safety of the new treatment.
Show me locations

The purpose

This is an open-label, multicenter, sequential, 5-arm, phase 1 study of oral IXAZOMIB designed to assess drug-drug interaction with ketoconazole (Arm 1), the relative bioavailability of 2 capsule formulations of IXAZOMIB (Arm 2), food effect (Arm 3), drug-drug interaction with rifampin (Arm 4), and drug-drug interaction with clarithromycin (Arm 5) in participants with advanced nonhematologic malignancies or lymphoma.

Provided treatments

  • Drug: Ixazomib 2.5 mg
  • Drug: Ixazomib 4 mg Capsule A
  • Drug: Ixazomib 4 mg Capsule B
  • Drug: Ketoconazole
  • Drug: Rifampin
  • Drug: Clarithromycin
  • Drug: Ixazomib 4 mg Capsule B

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01454076. The sponsor of the trial is Millennium Pharmaceuticals, Inc. and it is looking for 112 volunteers for the current phase.
Official trial title:
A Phase 1 Study of Oral IXAZOMIB (MLN9708) to Assess Relative Bioavailability, Food Effect, Drug-Drug Interaction With Ketoconazole, Clarithromycin or Rifampin; and Safety and Tolerability in Patients With Advanced Nonhematologic Malignancies or Lymphoma