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Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Chronic Schizophrenia or Schizoaffective Disorder
and you are
between 18 and 65
years old
This is a second phase trial assessing
efficacy and side effects of the new treatment.
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The purpose

This Phase I/IIa Proof-of-Concept (PoC) trial is designed to assess the effect of adding a single and repeated low dose (15mg/d) of pipamperone (PIP) for 6 weeks to stable treatment with an effective dose of risperidone (RIS) or paliperidone (PAL) on functional MRI tests and clinical outcome of chronic schizophrenic patients with residual, so-called 'positive' symptoms, as well as on cognition, motivation, subjective well-being of patients, negative symptoms, general psychopathological symptoms and safety/tolerability.

Provided treatments

  • Drug: Pipamperone
  • Drug: Placebo

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01450514. The sponsor of the trial is PharmaNeuroBoost N.V. and it is looking for 7 volunteers for the current phase.
Official trial title:
POC Study of Pipamperone 15mg Added to Stable Risperidone or Paliperidone Treatment in Chronic Schizophrenic and Schizoaffective Patients With Residual Symptoms: a Phase I/IIa, Randomized, Double-blind, Placebo-controlled Trial of 7 Weeks