Epilepsy is a chronic neurologic disorder characterized by seizures. Beside seizures people
suffering from epilepsy experience several challenges related to education, work and everyday
life such as learning-, problem-solving-, memory-, concentration-, attention difficulties and
It is generally approved that physical activity (PA) has a positive effect on physical as
well as mental factors. However, people with epilepsy are found to be less active and PA is
rarely offered or recommended as supplement to anti-epileptic medical treatment. Few studies
have investigated the effect of PA in subjects with epilepsy and additional studies of high
methodical quality are needed to enable evidence-based information and counselling.
This study is carried through as a randomized controlled trial which investigates the effect
of participation in a 10-week cardio exercise program in people with Juvenile Myoclonic
Epilepsy aged 15-50.
The study hypothesis is that participation in a 10-week cardio exercise program will induce a
positive change in cognitive function (concentration and attention) and possibly in
brain-derived neurotrophic factor (BDNF). In addition it is expected that the intensity and
duration of the 10-week cardio exercise program is sufficient to cause changes in
physiological parameters related to a reduced risk of lifestyle diseases.