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More info
You can access this
clinical trial
if you have
Ehlers-Danlos Syndrome, Classic
and you are
over 18
years old
The phase for this study is not defined.
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The purpose

The investigators want to inject insulin-like growth factor-I (IGF-I) into the patella tendon of Ehlers-Danlos patients and healthy controls to evaluate the response in collagen synthesis. Furthermore collagen synthesis is measured in muscle connective tissue and in skin. The hypothesis is that the connective tissue in Ehlers-Danlos patients is more compliant and poorer in collagen than healthy controls, but that collagen synthesis can be stimulated by IGF-I.

Provided treatments

  • Drug: mecasermin
  • Drug: Saline

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01446783. The sponsor of the trial is Bispebjerg Hospital and it is looking for 15 volunteers for the current phase.
Official trial title:
IGF-I Stimulation of Collagen Synthesis in Ehlers-Danlos Patients