Dexmedetomidine is a highly selective a2-adrenoreceptor agonist that produces dose-dependent
sedation and analgesia without respiratory depression. Dexmedetomidine has been used in
critically ill medical, surgical, and pediatric patients. No study has been designed
specifically to evaluate dexmedetomidine uses in the neurocritical care population. The
primary objective is to evaluate the safety and efficacy of dexmedetomidine for prophylactic
analgesia and sedation in patients after intracranial surgery.