The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and
pharmacodynamics of TRV120027 in subjects with heart failure and mild to moderate renal
Drug: Normal Saline
We will connect you to the doctor responsible for this trial and help you get more information.
Locations near you
Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Full eligibility criteria for NCT01444872
Ages eligible for Study
18 Years to 74 Years
Genders eligible for Study
Accepts Healthy Volunteers
Written Informed Consent
Mild to moderate renal dysfunction
Age 18- <75
Males and females (non-childbearing potential)
Any significant disease or condition that would interfere with the interpretation of safety or efficacy or efficacy data as determined by the Investigator based on medical history, physical examination or laboratory tests
Any other serious life threatening disease that may impair the interpretation of safety or efficacy data from the study as determined by the Investigator
Allergy or clinically-significant intolerance to ARBs or ACE inhibitors
Clinical signs or symptoms of acute decompensated heart failure
Pregnant or lactating
All locations for NCT01444872
United States (5)
Orlando Clinical Research Center
Orlando, Florida, United States, 32809
Kalamazoo, Michigan, United States, 49007
Minneapolis, Minnesota, United States, 55404
Duke Clinical Research Unit
Durham, North Carolina, United States, 27705
New Orleans Center for Clinical Research
Knoxville, Tennessee, United States, 37920
View full eligibility
Tris trial is registered with FDA with number: NCT01444872. The sponsor of the trial is Trevena Inc. and it is looking for 17 volunteers for the current phase.
Official trial title: A Randomized, Single-Blind, Placebo-Controlled, Adaptive, Ascending Dose Study to Evaluate the Effects of TRV120027 on Renal Pharmacodynamics in Patients With Heart Failure and Mild to Moderate Renal Dysfunction
1What's a trial
4Get in touch
What's a trial
Not sure you're well informed about clinical trials? Learn more about their benefits, risks and other important details.
Enter your details like condition, age, gender and other preferences and we will show you a list of all relevant clinical trials.
Review the summary of the selected clinical trial and all the locations near you in order to see if it's of interest to you.
Get in touch
You've found an interesting trial? We'll need a bit more information about you so we can connect you to the doctor in charge.
Some people want to consult their doctor before considering participation in a clinical trial. This is absolutely normal as your doctor should know your medical history and should be able to advise you. If you want you can easily share the information for this trial with your doctor by clicking on the button below.