Peripheral Arterial Disease (PAD) is a highly prevalent public health problem that results
from progressive atherosclerosis of arteries in the lower extremities. PAD is also associated
with major detrimental effects on quality of life and functional status, and is the most
important cause of limb amputation. More importantly, PAD is a major manifestation of
cardiovascular disease and a potent predictor of myocardial infarction, stroke and death.
Despite its frequent occurrence, little is known about the natural history of PAD in
Hispanics who represent 12.5% of the United States. Because access to health care is limited
among Hispanics, CBPR is the ideal process to reach this target population. The goal of the
proposed study is to evaluate community-based strategies of detection and treatment of
peripheral arterial disease (PAD) in Hispanics. The proposed project consists of two phases:
a cross-sectional phase (PAD detection), followed by a randomization phase.During the PAD
detection study , the prevalence and severity of PAD in this population will be determined.
Specific risk factors associated with PAD among the Hispanic participants will be identified.
During the second phase patients will be enrolled in a randomized, non-blinded trial
comparing a community-based risk factor modification and supervised exercise program versus
usual care for PAD. These individuals will undergo a baseline evaluation similar to the one
obtained during the first phase of the study, but will also include functional testing of the