The purpose of this study is to examine the effects of a gentle pressure movement performed
at the ankle by a physical therapist on muscle function and ankle motion in individuals who
frequently twist (sprain) their ankle.
Other: Small amplitude (Grade IV) mobilization
Other: High velocity, low amplitude (Grade V) mobilization
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Full eligibility criteria for NCT01438905
Ages eligible for Study
19 Years to 45 Years
Genders eligible for Study
Accepts Healthy Volunteers
Age 16-45 years
History of one or more ankle sprains
Scoring at least an 85% on the Foot and Ankle Ability Measure (FAAM) Sport or at least 3 on the Modified Ankle Instability Instrument (AII).
At least 5° ankle dorsiflexion asymmetry compared to the contralateral limb OR ankle dorsiflexion ROM less than 21°
Lower extremity injury or surgery within the past 6 months (including lateral ankle sprain)
Diagnosed ankle osteoarthritis
History of ankle surgery that involves intra-articular fixation
Medical conditions which would be contraindications to mobilization/manipulation and/or transcranial magnetic stimulation, including cardiac pacemaker, metal implants in the head, current pregnancy, neurological disorders, recent use of stimulants or medications known to lower seizure threshold, and personal or family history of seizures
All locations for NCT01438905
United States (1)
Omaha, Nebraska, United States, 68178
View full eligibility
Tris trial is registered with FDA with number: NCT01438905. The sponsor of the trial is Creighton University and it is looking for 30 volunteers for the current phase.
Official trial title: Effect of Joint Mobilization on Muscle Activation and Function in Individuals With Chronic Ankle Instability
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