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Your journey
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3Review
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More info
You can access this
clinical trial
if you have
Colorectal Cancer
and you are
between 40 and 80
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

Colorectal cancer is a major problem in the United States and other developed countries. A safe and effective chemopreventive agent could reduce the burden of colorectal neoplasia. Curcumin, is a product that is derived from Curcuma longa. It has been used for thousands of years as a traditional remedy. Curcumin blocks a number of targets involved in tumor initiation, promotion, and progression, and is considered a promising chemopreventive agent. The investigators propose to enroll 40 patients after screening colonoscopy who will have rectal biopsies at baseline and after 4 weeks of curcumin 4 grams per day. The investigators will use microarray analysis to identify genes that are modified by curcumin that could be used as biomarkers in future chemoprevention studies. The study will also evaluate tolerability and toxicity.

Provided treatments

  • Drug: Curcumin C3 tablet

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01333917. The sponsor of the trial is University of North Carolina, Chapel Hill and it is looking for 40 volunteers for the current phase.
Official trial title:
Curcumin Chemoprevention of Colorectal Neoplasia