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More info
You can access this
clinical trial
if you have
Pulmonary Disease or Cardiovascular Disease
and you are
between 14 and 80
years old
This is an observational trial.
You are contributing to medical knowledge about your condition.
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The purpose

The aim of this study is to assess in the sample of population resident in the KHUMBU valley (NEPAL): 1. the respiratory function decline by means of spirometry and the respiratory health by means of questionnaire and six-minute walking distance 2. the presence of markers of early atherosclerosis with ultrasound and to estimate the value of systolic pulmonary pressure in comparison with not exposed subjects. The investigators hypothesize that the chronic exposure to indoor pollution 1. can accelerate the physiological respiratory function decline, usually around 15-20mL/year in healthy subjects 2. induce cardiovascular impairment The population of high altitude villages is a unique sample to study the effect of the only indoor pollution. In fact, the absence of traffic, due to the lack of roads, and the very low level of smoking habits allow to have no other confounding factors 3. to study and analyze how the architectural features of the buildings of the village (distribution of domestic locals, natural or non natural ventilation systems, domestic activities, materials used, etc.) affect the indoor pollution from carbon monoxide, which necessarily is developed indoor during the daily life activities. What the project prospects is to gather information focused on the scale of the building, independently from the typology, to study a model that will help to describe which aspects are most important to what concern the genesis of the pollution of the indoor air.

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01329159. The sponsor of the trial is Università degli Studi di Ferrara and it is looking for 300 volunteers for the current phase.
Official trial title:
Cardio-Respiratory Health in High Altitude Residents Exposed to Indoor Pollution