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Your journey
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More info
You can access this
clinical trial
if you have
Decompensated Cirrhosis, Portal Vein Thrombosis or Bleeding Varices
and you are
between 18 and 75
years old
-
The phase for this study is not defined.
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The purpose

Portal vein thrombosis (PVT) refers to an obstruction in the trunk of the portal vein. It can extend downstream to the portal branches, or upstream to the splenic and/or the mesenteric veins. The prevalence of PVT is 10-25% and incidence is about 16% in cirrhotic patients. Recent studies demonstrate that the presence of PVT is not only an independent predictor of failure to control active variceal bleeding and prevent variceal rebleeding, but also significantly associated with increased mortality in patients with liver cirrhosis. However, in recent American Association of the Study of Liver Disease (AASLD) practice guidelines and Baveno V consensus, no treatment strategies in cirrhotic patients with PVT was clearly recommended due to the absence of randomized controlled trials.

Provided treatments

  • Procedure: Transjugular intrahepatic portosystemic shunt (TIPS)
  • Procedure: ET+NSBB

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01326949. The sponsor of the trial is Fourth Military Medical University and it is looking for 52 volunteers for the current phase.
Official trial title:
Transjugular Intrahepatic Portosystemic Shunt Versus Endoscopic Treatment Combined With Propranolol for Prevention of Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis: A Randomized Controlled Trial