Overweight and obesity has been associated with a number of adverse pregnancy outcomes in
women of reproductive age, including infertility and early pregnancy loss. Recent data
suggests that overweight and obese patients are also at increased risk of recurrent pregnancy
loss (RPL), a devastating condition that affects 1% of the fertile population.
The investigators propose a prospective, randomized controlled trial in which overweight and
obese patients with unexplained recurrent pregnancy loss are enrolled in a structured, 6
month, weight loss program or provided routine counseling regarding the importance of weight
loss. Pregnancy outcomes will then be followed to assess miscarriage rates. Metabolic
outcomes, such as lipid and glucose profiles, will also be evaluated.