The association between exposure to ambient air pollution and pulmonary disease has been well
established.To date no study has assessed the burden of cardiovascular disease in Israel and
its relation to ambient air pollution.
The Haifa Bay Area has a long history of industrialization including possessing the nation's
largest oil refineries, oil-fired power plant, agrochemical and cement producers, industrial
incinerators and the Eastern Mediterranean's busiest port. The presence of industrial and
mobile sources, combined with a basin effect has contributed to air pollution in the Haifa
Bay Area and has raised concerns about potential health effects.
- Determine if the increased rate of cardiovascular mortality in Haifa is associated with
PM 2.5 concentrations.
- Assess effect modification in diverse sub-populations.
- If an association does exist, assess the economic burden of PM 2.5 associated
cardiovascular morbidity and mortality.
- Design prediction models of daily cardiovascular emergency department visits based on
daily and seasonal variation of air pollution.