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More info
You can access this
clinical trial
if you have
Salt-sensitive Hypertension
and you are
between 18 and 55
years old
The phase for this study is not defined.
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The purpose

The kidney plays a crucial role in maintaining salt balance by two opposing physiological mechanisms: the renal dopaminergic system which enhances salt excretion and the renin-angiotensin system (RAS) which causes salt retention. Salt-sensitive hypertension occurs when this balance is altered or abnormal. We hypothesized that this balance is influenced by salt intake: therefore dietary salt affects the natriuretic response to the renal dopaminergic agonist Fenoldopam, and the Angiotensin Converting Enzyme inhibitor, Enalapril. In this trial we study normal salt balance mechanisms in salt resistant adults with normal blood pressure.

Provided treatments

  • Drug: Fenoldopam

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01324245. The sponsor of the trial is Georgetown University and it is looking for 45 volunteers for the current phase.
Official trial title:
Paracrine Regulation of Renal Function by Dopamine in Normotensive Humans