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More info
You can access this
clinical trial
if you have
Parkinson Disease
and you are
between 18 and 75
years old
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

This is a two part study to compare the PK of preladenant administered to participants with CRI to the PK of preladenant administered to healthy participants. Part 1 will compare the PK of participants with severe CRI to healthy participants. Part 2 will compare the PK of participants with moderate CRI and participants with mild CRI to healthy participants. The primary hypotheses are that the plasma area under the concentration-time curve from time 0 to infinity after single dosing (AUC0-∞) of preladenant in participants with either severe, moderate or mild CRI is similar to that of matched healthy participants.

Provided treatments

  • Drug: Preladenant

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01323855. The sponsor of the trial is Merck Sharp & Dohme Corp. and it is looking for 46 volunteers for the current phase.
Official trial title:
A Study to Assess Pharmacokinetics of Preladenant in Subjects With Chronic Renal Impairment