While narcotic medication are commonly used for pain control near the time of surgery, there
are significant side effects including constipation, nausea, risk of overdose leading to
decreased breathing, and risk of addiction to narcotics. Our goal is to explore alternatives
to narcotics for perioperative pain for patients undergoing sperm retrieval surgery. We have
designed a prospective randomized clinical trial to evaluate how effective the
anti-inflammatory medicine celecoxib(Celebrex©) is for pain control near the time of surgery.
Celecoxib is known as a COX-2 inhibitor, a drug that belongs to the non-steroidal
anti-inflammatory drug (NSAID) class. It is used to reduce swelling and to treat pain.
Patients will be divided into two groups: the first group receives a celecoxib pill and the
second group receives a sugar pill(placebo). Patients and doctors will be unaware of exactly
which pills are given. The patient will complete questionnaires for pain level. By comparing
the pain levels we can better understand whether celecoxib (Celebrex©) significantly
decreases perioperative pain.