Obstructive sleep apnea/hypopnea syndrome (OSAHS) is a highly prevalent disorder with
OSAHS is characterized by repetitive episodes of airflow reduction (hypopnoea) or cessation
(apnoea) due to upper airway collapse during sleep. Its major risk factor is obesity.
However, its pathogenesis is complex and multifactorial. Reduced upper airway muscle tonus
and/or unstable neuromuscular output seem to be involved in this collapsus.
A normal vitamin D status is necessary for normal muscle function and neuromuscular output.
As obesity is associated with a high rate of hypovitaminosis D, it appears of interest to
evaluate the effect of vitamin D supplementation on OSAHS patients with vitamin D deficiency.