This trial is terminated!
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Your journey
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More info
You can access this
clinical trial
if you have
Brain Metastases or CNS Metastases
and you are
over 18
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

Because electrochemotherapy is a quick and effective treatment for cutaneous metastases, a novel electrode device has been developed for treatment in soft tissue such as the brain. Up to 18 patients will be treated in this phase I dose-escalating study of electrochemotherapy for brain metastases. Primary endpoint of the clinical trial is safety and secondary endpoint is efficacy. One brain metastasis is treated once-only with the electrode device guided stereotactically through a burr hole using CT monitoring. The patient will be fully anesthetized during the treatment procedure. Patients are followed up for 6 months with regard to neurological function, Barthel Index, steroid use and adverse effects registration (CTCAE). Tumor response will be evaluated by Magnetic Resonance imaging (MRI).

Provided treatments

  • Device: The Electroporation System
  • Drug: Bleomycin

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01322100. The sponsor of the trial is Copenhagen University Hospital at Herlev and it is looking for 1 volunteers for the current phase.
Official trial title:
Electrochemotherapy as a Palliative Treatment for Brain Metastases