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Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Brain Injuries, Craniocerebral Trauma, Trauma, Nervous System or Traumatic Brain Injury
and you are
between 16 and 64
years old
This is a second phase trial assessing
efficacy and side effects of the new treatment.
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The purpose

The investigators intend to determine the effect of adrenergic blockade on 1) short-term physiology, behavior, and cognition and 2) long-term neuropsychological outcomes after severe Traumatic Brain Injury (TBI). The primary hypothesis is that adrenergic blockade after severe TBI will be associated with increased ventilator-free days.

Provided treatments

  • Drug: IV Propranolol and Per Tube Clonidine
  • Drug: Placebo

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01322048. The sponsor of the trial is Vanderbilt University and it is looking for 48 volunteers for the current phase.
Official trial title:
DASH After TBI Study: Decreasing Adrenergic or Sympathetic Hyperactivity After Severe Traumatic Brain Injury, A Pilot Randomized Clinical Trial Using Propranolol and Clonidine