The primary hypothesis for this study is that Myostatin and FHL-1 are important in the
development of ICUAP and that changes in activity levels of muscle will modify the levels of
expression and activity of these proteins.
Other: Active muscle stimulation
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Locations near you
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Full eligibility criteria for NCT01321320
Ages eligible for Study
18 Years and older
Genders eligible for Study
Accepts Healthy Volunteers
High risk patients admitted to AICU.
Pre existing neuromuscular disease.
All locations for NCT01321320
United Kingdom (1)
National Heart and Lung Institute, Imperial College
London, United Kingdom
View full eligibility
Tris trial is registered with FDA with number: NCT01321320. The sponsor of the trial is Imperial College London and it is looking for 13 volunteers for the current phase.
Official trial title: Investigation of the Role of FHL-1 and Myostatin in the Development of Intensive Care Unit Acquired Paresis (ICUAP) and the Effect of Increased Muscle Activity on These Pathways.
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