The purpose of this prospective study is determine if barbed sutures are more efficient, have
comparable complication rates, clinical outcomes, and cosmesis outcomes versus traditional
knotted sutures when used in the closure of primary total knee arthroplasty (TKA).
Barbed suture has been associated with improved closure efficiency and safety in TKA in prior
studies. The investigators performed a multicenter randomized controlled trial to determine
the efficiency and safety of this technology in TKA. The investigators prospectively
randomized 411 patients undergoing primary TKA to either barbed running (n=191) or knotted
interrupted suture closure (n=203). Closure time was measured intraoperatively. Cost analysis
was based on suture and operating room time costs.