The aim of the study is to assess the accuracy of real-time perfusion imaging pattern of
pancreatic focal lesions visualized by contrast-enhanced harmonic endoscopic ultrasound
(CEH-EUS) for the differential diagnosis between chronic pseudotumoral pancreatitis and
pancreatic cancer in a prospective multicenter design.
The study will include patients with focal pancreatic masses evaluated by CEH-EUS and
EUS-FNA. The diagnosis is usually unknown in the moment of the initial evaluation, the
patients being included based on a suspicion of focal pancreatic masses after transabdominal
ultrasound, CT or MR examinations. However, after a complete evaluation, a final diagnosis
will be reached based on the combination of EUS-FNA cytology/pathology, surgical pathology
and minimum 12 months follow-up.