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More info
You can access this
clinical trial
if you have
Healthy Volunteers
and you are
between 18 and 55
years old
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

24-hr urinary sodium/potassium ratio will be a sensitive biomarker of antimineralocorticoid activity. The dose-response relationship of the antimineralocorticoid activity of PF-03882845 can be established following single oral doses.

Provided treatments

  • Drug: 3 mg PF-03882845
  • Drug: 10 mg PF-03882845
  • Drug: 30 mg PF-03882845
  • Drug: 100 mg PF-03882845
  • Drug: Spironolactone

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01314898. The sponsor of the trial is Pfizer and it is looking for 12 volunteers for the current phase.
Official trial title:
A Phase 1, Double-Blind (Sponsor-Open), Placebo- And Active-Controlled, Single Dose, Crossover Study To Assess Antimineralocorticoid Activity Of Oral Pf-03882845 In Healthy Subjects.