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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Healthy Volunteers or Pharmacokinetics/Dynamics Study
and you are
between 18 and 45
years old
This is a second phase trial assessing
efficacy and side effects of the new treatment.
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The purpose

Pharmacokinetics, pharmacodynamics and tolerability of AOP200704 infusion is compared to that of Esmolol by measurement of plasma concentrations of AOP200704, esmolol and their metabolites, by assessing the effect of both drugs on dobutamine-induced tachycardia, and by monitoring vital signs, ECG and adverse events.

Provided treatments

  • Drug: AOP200704
  • Drug: Esmolol hydrochloride, infusion

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01313143. The sponsor of the trial is AOP Orphan Pharmaceuticals AG and it is looking for 16 volunteers for the current phase.
Official trial title:
A Prospective, Randomized, Double Blinded, Crossover, Two-treatment, Two-sequence, Short Term Pharmacokinetic, Pharmacodynamic and Tolerability, Single Centre Study to Compare AOP200704 vs. Esmolol in Healthy Subjects.