The purpose of this study is to help us learn what the best amount of fluid is that patients
should receive during pancreas surgery. Patients will receive either the liberal fluid amount
for this surgery or a restricted fluid amount.
Both amounts of fluid have been used safely in patients having similar surgeries. These
amounts have not been compared in pancreatic surgery. The fluids regimens that will be given
are not experimental.
This study will compare patients in the liberal and restricted fluid groups in terms of the
nature of any surgical complications (problems)and recovery from surgery, including length of
Other: restrictive perioperative fluid management
Other: Liberal perioperative fluid management
We will connect you to the doctor responsible for this trial and help you get more information.
Locations near you
Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Full eligibility criteria for NCT01058746
Ages eligible for Study
18 Years and older
Genders eligible for Study
Accepts Healthy Volunteers
Adults > or = 18 years
Patients scheduled for Pancreaticoduodenectomy, Central Pancreatectomy or Distal Pancreatectomy.
History of active coronary disease unless a cardiac stress test showing no reversible ischemia and normal LV function within 30 days of operation
MI within 3 months
History of stroke
History of congestive heart failure and ejection fraction less than 35%
History of severe COPD and resting oxygen saturation (SpO2) < 90%
Renal dysfunction (Cr > 1.8)
Abnormal coagulation parameters (INR > 1.5 not on Coumadin, or platelet
Presence of active infection including HIV
BMI > 35
American Society of Anesthesiologists Status > III, assigned at time of preoperative visit
Corticosteroid use > 10 mg Prednisone/day
Bilirubin > 10.0
All locations for NCT01058746
United States (1)
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
View full eligibility
Tris trial is registered with FDA with number: NCT01058746. The sponsor of the trial is Memorial Sloan Kettering Cancer Center and it is looking for 331 volunteers for the current phase.
Official trial title: A Prospective Randomized Controlled Clinical Trial of Restrictive Versus Liberal Perioperative Fluid Management for Patients Undergoing Pancreatic Resection
1What's a trial
4Get in touch
What's a trial
Not sure you're well informed about clinical trials? Learn more about their benefits, risks and other important details.
Enter your details like condition, age, gender and other preferences and we will show you a list of all relevant clinical trials.
Review the summary of the selected clinical trial and all the locations near you in order to see if it's of interest to you.
Get in touch
You've found an interesting trial? We'll need a bit more information about you so we can connect you to the doctor in charge.
Thank you for applying!
We'll contact you soon with more information.
Consult your doctor?
Some people want to consult their doctor before considering participation in a clinical trial. This is absolutely normal as your doctor should know your medical history and should be able to advise you. If you want you can easily share the information for this trial with your doctor by clicking on the button below.