This is a randomized clinical trial designed to evaluate oral nitazoxanide compared to a
placebo in the treatment of acute uncomplicated influenza in adults. We hypothesize that
treatment with nitazoxanide will reduce the duration of symptoms in patients with confirmed
influenza infection. Secondarily, we hypothesize that treatment with nitazoxanide will reduce
the complications of influenza, severity of symptoms, time lost from work, time to return to
normal daily activities, and viral shedding.